Pavel Kovarik Selected Research

Tristetraprolin

1/2021	Conceptual Advances in Control of Inflammation by the RNA-Binding Protein Tristetraprolin.
6/2017	The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.
1/2016	Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution.
12/2011	Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation.
1/2007	Molecular mechanisms of the anti-inflammatory functions of interferons.
6/2006	Interferons limit inflammatory responses by induction of tristetraprolin.

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Pavel Kovarik Research Topics

Disease

10	Inflammation (Inflammations) 11/2021 - 06/2006
7	Infections 01/2022 - 01/2007
4	Neoplasms (Cancer) 11/2019 - 01/2007
3	Bacterial Infections (Bacterial Infection) 06/2017 - 01/2016
2	Shock 11/2021 - 05/2003
2	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2014 - 05/2011
2	Septic Shock (Toxic Shock Syndrome) 03/2010 - 05/2003
1	Osteomyelitis 01/2020
1	Chronic recurrent multifocal osteomyelitis 01/2020
1	Vulvovaginal Candidiasis 12/2018
1	B-Cell Leukemia (Leukemia, B Cell) 06/2017
1	Lymphoma (Lymphomas) 06/2017
1	Leukemia 06/2017
1	Soft Tissue Infections 06/2017
1	Adenoma (Adenomas) 01/2017
1	Colonic Neoplasms (Colon Cancer) 01/2017
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Weight Loss (Weight Reduction) 01/2017
1	B-Cell Lymphoma (Lymphoma, B Cell) 12/2016
1	Bites and Stings (Sting) 05/2011
1	Crohn Disease (Crohn's Disease) 07/2009
1	Rheumatoid Arthritis 07/2009
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2007
1	Multiple Sclerosis 01/2007

Drug/Important Bio-Agent (IBA)

7	CytokinesIBA 11/2021 - 01/2007
7	thiamine triphosphorate (TTP)IBA 01/2021 - 06/2006
6	TristetraprolinIBA 01/2021 - 06/2006
4	Interferon Type IIBA 11/2017 - 05/2003
3	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2021 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2016
3	InterferonsIBA 11/2019 - 06/2006
2	Messenger RNA (mRNA)IBA 01/2016 - 08/2015
2	Pattern Recognition ReceptorsIBA 01/2014 - 05/2011
2	LipopolysaccharidesIBA 03/2010 - 05/2003
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2022
1	sharpinIBA 11/2021
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 11/2021
1	UbiquitinIBA 11/2021
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2020
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2020
1	RNA Polymerase II (RNA Polymerase B)IBA 11/2019
1	Phosphotransferases (Kinase)IBA 11/2019
1	AzolesIBA 12/2018
1	Chemokine CCL11IBA 01/2017
1	5,8- dihydroxy- 3- methyl- 4- (9H)- naphtho(2,3- c)furanoneIBA 01/2017
1	16S Ribosomal RNAIBA 01/2017
1	Interleukin-18 (Interleukin 18)IBA 01/2017
1	Antiviral Agents (Antivirals)IBA 03/2016
1	RNA (Ribonucleic Acid)IBA 01/2016
1	ChemokinesIBA 08/2015
1	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2014
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2014
1	p38 Mitogen-Activated Protein KinasesIBA 12/2011
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 05/2011
1	STAT1 Transcription FactorIBA 09/2010
1	Janus KinasesIBA 03/2010
1	Interferon-alpha (Interferon Alfa)IBA 03/2010
1	TYK2 Kinase (Tyrosine Kinase 2)IBA 03/2010
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2009
1	Interleukin-10 (Interleukin 10)IBA 07/2009
1	Interleukin-1 (Interleukin 1)IBA 01/2007
1	Interleukin-4 (Interleukin 4)IBA 01/2007
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2003

Therapy/Procedure

1	Indwelling Catheters (Indwelling Catheter) 12/2018
1	Intraperitoneal Injections 01/2017